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A mimic of bronchogenic carcinoma - pulmonary melioidosis

We report a case of a patient with pulmonary melioidosis which radiologically mirrored a bronchogenic carcinoma with mediastinal lymphadenopathy. Such findings were observed in a Computed Tomography (CT) scan (Thorax) and Positron Emission Tomography (PET) scan (Body) in a previously healthy 57-year...

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Detalles Bibliográficos
Autores principales: Zhao, Joseph, Yap, Ashton, Wu, Eric, Yap, Jane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6997614/
https://www.ncbi.nlm.nih.gov/pubmed/32025484
http://dx.doi.org/10.1016/j.rmcr.2020.101006
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author Zhao, Joseph
Yap, Ashton
Wu, Eric
Yap, Jane
author_facet Zhao, Joseph
Yap, Ashton
Wu, Eric
Yap, Jane
author_sort Zhao, Joseph
collection PubMed
description We report a case of a patient with pulmonary melioidosis which radiologically mirrored a bronchogenic carcinoma with mediastinal lymphadenopathy. Such findings were observed in a Computed Tomography (CT) scan (Thorax) and Positron Emission Tomography (PET) scan (Body) in a previously healthy 57-year-old man with no significant medical risk factors for melioidosis other than his previous exposures to soil during outfield military training in Thailand, 37 and 28 years ago. He presented with acute symptoms of dry cough, pleuritic pain and fever. A CT Scan thorax revealed a left lower lobe mass with left pleural and pericardial effusion and mediastinal lymph nodes. Similarly, the PET scan showed various fluorodeoxyglucose (FDG)-positron uptake in these areas. However the lung mass biopsy cultured Burkholderia pseudomallei concurrently with a Melioidosis serology titre of >1:1024. He responded to intravenous Meropenem followed by Co-Trimoxazole and Doxycycline over the course of 21 weeks, ultimately leading to the resolution of any significant radiological findings.
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spelling pubmed-69976142020-02-05 A mimic of bronchogenic carcinoma - pulmonary melioidosis Zhao, Joseph Yap, Ashton Wu, Eric Yap, Jane Respir Med Case Rep Case Report We report a case of a patient with pulmonary melioidosis which radiologically mirrored a bronchogenic carcinoma with mediastinal lymphadenopathy. Such findings were observed in a Computed Tomography (CT) scan (Thorax) and Positron Emission Tomography (PET) scan (Body) in a previously healthy 57-year-old man with no significant medical risk factors for melioidosis other than his previous exposures to soil during outfield military training in Thailand, 37 and 28 years ago. He presented with acute symptoms of dry cough, pleuritic pain and fever. A CT Scan thorax revealed a left lower lobe mass with left pleural and pericardial effusion and mediastinal lymph nodes. Similarly, the PET scan showed various fluorodeoxyglucose (FDG)-positron uptake in these areas. However the lung mass biopsy cultured Burkholderia pseudomallei concurrently with a Melioidosis serology titre of >1:1024. He responded to intravenous Meropenem followed by Co-Trimoxazole and Doxycycline over the course of 21 weeks, ultimately leading to the resolution of any significant radiological findings. Elsevier 2020-01-26 /pmc/articles/PMC6997614/ /pubmed/32025484 http://dx.doi.org/10.1016/j.rmcr.2020.101006 Text en © 2020 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Zhao, Joseph
Yap, Ashton
Wu, Eric
Yap, Jane
A mimic of bronchogenic carcinoma - pulmonary melioidosis
title A mimic of bronchogenic carcinoma - pulmonary melioidosis
title_full A mimic of bronchogenic carcinoma - pulmonary melioidosis
title_fullStr A mimic of bronchogenic carcinoma - pulmonary melioidosis
title_full_unstemmed A mimic of bronchogenic carcinoma - pulmonary melioidosis
title_short A mimic of bronchogenic carcinoma - pulmonary melioidosis
title_sort mimic of bronchogenic carcinoma - pulmonary melioidosis
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6997614/
https://www.ncbi.nlm.nih.gov/pubmed/32025484
http://dx.doi.org/10.1016/j.rmcr.2020.101006
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