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A mimic of bronchogenic carcinoma - pulmonary melioidosis
We report a case of a patient with pulmonary melioidosis which radiologically mirrored a bronchogenic carcinoma with mediastinal lymphadenopathy. Such findings were observed in a Computed Tomography (CT) scan (Thorax) and Positron Emission Tomography (PET) scan (Body) in a previously healthy 57-year...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6997614/ https://www.ncbi.nlm.nih.gov/pubmed/32025484 http://dx.doi.org/10.1016/j.rmcr.2020.101006 |
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author | Zhao, Joseph Yap, Ashton Wu, Eric Yap, Jane |
author_facet | Zhao, Joseph Yap, Ashton Wu, Eric Yap, Jane |
author_sort | Zhao, Joseph |
collection | PubMed |
description | We report a case of a patient with pulmonary melioidosis which radiologically mirrored a bronchogenic carcinoma with mediastinal lymphadenopathy. Such findings were observed in a Computed Tomography (CT) scan (Thorax) and Positron Emission Tomography (PET) scan (Body) in a previously healthy 57-year-old man with no significant medical risk factors for melioidosis other than his previous exposures to soil during outfield military training in Thailand, 37 and 28 years ago. He presented with acute symptoms of dry cough, pleuritic pain and fever. A CT Scan thorax revealed a left lower lobe mass with left pleural and pericardial effusion and mediastinal lymph nodes. Similarly, the PET scan showed various fluorodeoxyglucose (FDG)-positron uptake in these areas. However the lung mass biopsy cultured Burkholderia pseudomallei concurrently with a Melioidosis serology titre of >1:1024. He responded to intravenous Meropenem followed by Co-Trimoxazole and Doxycycline over the course of 21 weeks, ultimately leading to the resolution of any significant radiological findings. |
format | Online Article Text |
id | pubmed-6997614 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-69976142020-02-05 A mimic of bronchogenic carcinoma - pulmonary melioidosis Zhao, Joseph Yap, Ashton Wu, Eric Yap, Jane Respir Med Case Rep Case Report We report a case of a patient with pulmonary melioidosis which radiologically mirrored a bronchogenic carcinoma with mediastinal lymphadenopathy. Such findings were observed in a Computed Tomography (CT) scan (Thorax) and Positron Emission Tomography (PET) scan (Body) in a previously healthy 57-year-old man with no significant medical risk factors for melioidosis other than his previous exposures to soil during outfield military training in Thailand, 37 and 28 years ago. He presented with acute symptoms of dry cough, pleuritic pain and fever. A CT Scan thorax revealed a left lower lobe mass with left pleural and pericardial effusion and mediastinal lymph nodes. Similarly, the PET scan showed various fluorodeoxyglucose (FDG)-positron uptake in these areas. However the lung mass biopsy cultured Burkholderia pseudomallei concurrently with a Melioidosis serology titre of >1:1024. He responded to intravenous Meropenem followed by Co-Trimoxazole and Doxycycline over the course of 21 weeks, ultimately leading to the resolution of any significant radiological findings. Elsevier 2020-01-26 /pmc/articles/PMC6997614/ /pubmed/32025484 http://dx.doi.org/10.1016/j.rmcr.2020.101006 Text en © 2020 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Case Report Zhao, Joseph Yap, Ashton Wu, Eric Yap, Jane A mimic of bronchogenic carcinoma - pulmonary melioidosis |
title | A mimic of bronchogenic carcinoma - pulmonary melioidosis |
title_full | A mimic of bronchogenic carcinoma - pulmonary melioidosis |
title_fullStr | A mimic of bronchogenic carcinoma - pulmonary melioidosis |
title_full_unstemmed | A mimic of bronchogenic carcinoma - pulmonary melioidosis |
title_short | A mimic of bronchogenic carcinoma - pulmonary melioidosis |
title_sort | mimic of bronchogenic carcinoma - pulmonary melioidosis |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6997614/ https://www.ncbi.nlm.nih.gov/pubmed/32025484 http://dx.doi.org/10.1016/j.rmcr.2020.101006 |
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