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In-vitro antibacterial, antioxidant potentials and cytotoxic activity of the leaves of Tridax procumbens

The present study explored the phytochemicals, antibacterial, antioxidant and cytotoxic effect of Tridax procumbens leaves. The leaves were dried and extracted with various organic solvents. The leaves contained the phytochemicals such as alkaloids, carbohydrates, polyphenols and tannins respectivel...

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Detalles Bibliográficos
Autores principales: Syed, Asad, Benit, Natarajan, Alyousef, Abdullah A., Alqasim, Abdulaziz, Arshad, Mohammed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6997847/
https://www.ncbi.nlm.nih.gov/pubmed/32210697
http://dx.doi.org/10.1016/j.sjbs.2019.12.031
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author Syed, Asad
Benit, Natarajan
Alyousef, Abdullah A.
Alqasim, Abdulaziz
Arshad, Mohammed
author_facet Syed, Asad
Benit, Natarajan
Alyousef, Abdullah A.
Alqasim, Abdulaziz
Arshad, Mohammed
author_sort Syed, Asad
collection PubMed
description The present study explored the phytochemicals, antibacterial, antioxidant and cytotoxic effect of Tridax procumbens leaves. The leaves were dried and extracted with various organic solvents. The leaves contained the phytochemicals such as alkaloids, carbohydrates, polyphenols and tannins respectively. Antimicrobial potentials of the extracts were determined by performing the disc diffusion techniques. Results revealed that different organic solvents extracts namely methanol, ethanol and ethyl acetate extracts documented comparatively good activity against the studied microbial strains. The methanol extract of leaves of T. procumbens showed combatively better antioxidant potential. The tested plant leaf extract showed high activity against human lung cancer cells than breast cancer cell lines. 250 µg/ml plants extract showed 84 ± 2.8% toxicity against human lung cancer cells.
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spelling pubmed-69978472020-03-24 In-vitro antibacterial, antioxidant potentials and cytotoxic activity of the leaves of Tridax procumbens Syed, Asad Benit, Natarajan Alyousef, Abdullah A. Alqasim, Abdulaziz Arshad, Mohammed Saudi J Biol Sci Article The present study explored the phytochemicals, antibacterial, antioxidant and cytotoxic effect of Tridax procumbens leaves. The leaves were dried and extracted with various organic solvents. The leaves contained the phytochemicals such as alkaloids, carbohydrates, polyphenols and tannins respectively. Antimicrobial potentials of the extracts were determined by performing the disc diffusion techniques. Results revealed that different organic solvents extracts namely methanol, ethanol and ethyl acetate extracts documented comparatively good activity against the studied microbial strains. The methanol extract of leaves of T. procumbens showed combatively better antioxidant potential. The tested plant leaf extract showed high activity against human lung cancer cells than breast cancer cell lines. 250 µg/ml plants extract showed 84 ± 2.8% toxicity against human lung cancer cells. Elsevier 2020-02 2019-12-26 /pmc/articles/PMC6997847/ /pubmed/32210697 http://dx.doi.org/10.1016/j.sjbs.2019.12.031 Text en © 2019 Published by Elsevier B.V. on behalf of King Saud University. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Article
Syed, Asad
Benit, Natarajan
Alyousef, Abdullah A.
Alqasim, Abdulaziz
Arshad, Mohammed
In-vitro antibacterial, antioxidant potentials and cytotoxic activity of the leaves of Tridax procumbens
title In-vitro antibacterial, antioxidant potentials and cytotoxic activity of the leaves of Tridax procumbens
title_full In-vitro antibacterial, antioxidant potentials and cytotoxic activity of the leaves of Tridax procumbens
title_fullStr In-vitro antibacterial, antioxidant potentials and cytotoxic activity of the leaves of Tridax procumbens
title_full_unstemmed In-vitro antibacterial, antioxidant potentials and cytotoxic activity of the leaves of Tridax procumbens
title_short In-vitro antibacterial, antioxidant potentials and cytotoxic activity of the leaves of Tridax procumbens
title_sort in-vitro antibacterial, antioxidant potentials and cytotoxic activity of the leaves of tridax procumbens
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6997847/
https://www.ncbi.nlm.nih.gov/pubmed/32210697
http://dx.doi.org/10.1016/j.sjbs.2019.12.031
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