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In-vitro antibacterial, antioxidant potentials and cytotoxic activity of the leaves of Tridax procumbens
The present study explored the phytochemicals, antibacterial, antioxidant and cytotoxic effect of Tridax procumbens leaves. The leaves were dried and extracted with various organic solvents. The leaves contained the phytochemicals such as alkaloids, carbohydrates, polyphenols and tannins respectivel...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6997847/ https://www.ncbi.nlm.nih.gov/pubmed/32210697 http://dx.doi.org/10.1016/j.sjbs.2019.12.031 |
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author | Syed, Asad Benit, Natarajan Alyousef, Abdullah A. Alqasim, Abdulaziz Arshad, Mohammed |
author_facet | Syed, Asad Benit, Natarajan Alyousef, Abdullah A. Alqasim, Abdulaziz Arshad, Mohammed |
author_sort | Syed, Asad |
collection | PubMed |
description | The present study explored the phytochemicals, antibacterial, antioxidant and cytotoxic effect of Tridax procumbens leaves. The leaves were dried and extracted with various organic solvents. The leaves contained the phytochemicals such as alkaloids, carbohydrates, polyphenols and tannins respectively. Antimicrobial potentials of the extracts were determined by performing the disc diffusion techniques. Results revealed that different organic solvents extracts namely methanol, ethanol and ethyl acetate extracts documented comparatively good activity against the studied microbial strains. The methanol extract of leaves of T. procumbens showed combatively better antioxidant potential. The tested plant leaf extract showed high activity against human lung cancer cells than breast cancer cell lines. 250 µg/ml plants extract showed 84 ± 2.8% toxicity against human lung cancer cells. |
format | Online Article Text |
id | pubmed-6997847 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-69978472020-03-24 In-vitro antibacterial, antioxidant potentials and cytotoxic activity of the leaves of Tridax procumbens Syed, Asad Benit, Natarajan Alyousef, Abdullah A. Alqasim, Abdulaziz Arshad, Mohammed Saudi J Biol Sci Article The present study explored the phytochemicals, antibacterial, antioxidant and cytotoxic effect of Tridax procumbens leaves. The leaves were dried and extracted with various organic solvents. The leaves contained the phytochemicals such as alkaloids, carbohydrates, polyphenols and tannins respectively. Antimicrobial potentials of the extracts were determined by performing the disc diffusion techniques. Results revealed that different organic solvents extracts namely methanol, ethanol and ethyl acetate extracts documented comparatively good activity against the studied microbial strains. The methanol extract of leaves of T. procumbens showed combatively better antioxidant potential. The tested plant leaf extract showed high activity against human lung cancer cells than breast cancer cell lines. 250 µg/ml plants extract showed 84 ± 2.8% toxicity against human lung cancer cells. Elsevier 2020-02 2019-12-26 /pmc/articles/PMC6997847/ /pubmed/32210697 http://dx.doi.org/10.1016/j.sjbs.2019.12.031 Text en © 2019 Published by Elsevier B.V. on behalf of King Saud University. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Article Syed, Asad Benit, Natarajan Alyousef, Abdullah A. Alqasim, Abdulaziz Arshad, Mohammed In-vitro antibacterial, antioxidant potentials and cytotoxic activity of the leaves of Tridax procumbens |
title | In-vitro antibacterial, antioxidant potentials and cytotoxic activity of the leaves of Tridax procumbens |
title_full | In-vitro antibacterial, antioxidant potentials and cytotoxic activity of the leaves of Tridax procumbens |
title_fullStr | In-vitro antibacterial, antioxidant potentials and cytotoxic activity of the leaves of Tridax procumbens |
title_full_unstemmed | In-vitro antibacterial, antioxidant potentials and cytotoxic activity of the leaves of Tridax procumbens |
title_short | In-vitro antibacterial, antioxidant potentials and cytotoxic activity of the leaves of Tridax procumbens |
title_sort | in-vitro antibacterial, antioxidant potentials and cytotoxic activity of the leaves of tridax procumbens |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6997847/ https://www.ncbi.nlm.nih.gov/pubmed/32210697 http://dx.doi.org/10.1016/j.sjbs.2019.12.031 |
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