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A Non-canonical Function of BMAL1 Metabolically Limits Obesity-Promoted Triple-Negative Breast Cancer

The epidemiological association between disrupted circadian rhythms and metabolic diseases is implicated in increased risk of human breast cancer and poor therapeutic outcomes. To define a metabolic phenotype and the underlying molecular mechanism, we applied chronic insulin treatment (CIT) to an in...

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Detalles Bibliográficos
Autores principales: Ramos, Cassandra A., Ouyang, Ching, Qi, Yue, Chung, Yiyin, Cheng, Chun-Ting, LaBarge, Mark A., Seewaldt, Victoria L., Ann, David K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6997869/
https://www.ncbi.nlm.nih.gov/pubmed/32058954
http://dx.doi.org/10.1016/j.isci.2020.100839