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A Non-canonical Function of BMAL1 Metabolically Limits Obesity-Promoted Triple-Negative Breast Cancer
The epidemiological association between disrupted circadian rhythms and metabolic diseases is implicated in increased risk of human breast cancer and poor therapeutic outcomes. To define a metabolic phenotype and the underlying molecular mechanism, we applied chronic insulin treatment (CIT) to an in...
Autores principales: | Ramos, Cassandra A., Ouyang, Ching, Qi, Yue, Chung, Yiyin, Cheng, Chun-Ting, LaBarge, Mark A., Seewaldt, Victoria L., Ann, David K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6997869/ https://www.ncbi.nlm.nih.gov/pubmed/32058954 http://dx.doi.org/10.1016/j.isci.2020.100839 |
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