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Review of metastatic colorectal cancer treatment pathways and early clinical experience of trifluridine/tipiracil in the UK named patient programme

BACKGROUND: The standard first- and second- line chemotherapy backbone regimens for metastatic colorectal cancer (mCRC) are 5-fluorouracil (5-FU)/capecitabine-based with addition of irinotecan or oxaliplatin. Until recently, evidence for optimal sequencing post second-line was sparse. Trifluridine/t...

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Detalles Bibliográficos
Autores principales: Iveson, Timothy, Carter, Angela M., Shiu, Kai-Keen, Spooner, Clare, Stevens, Daniel, Mullamitha, Saifee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6998075/
https://www.ncbi.nlm.nih.gov/pubmed/32013902
http://dx.doi.org/10.1186/s12885-020-6577-1

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