SIRT7 depletion inhibits cell proliferation and androgen-induced autophagy by suppressing the AR signaling in prostate cancer

BACKGROUND: Sirtuin-7 (SIRT7) is associated with the maintenance of tumorigenesis. However, its functional roles and oncogenic mechanisms in prostate cancer (PCa) are poorly understood. Here, we investigated the roles and underlying molecular mechanisms of SIRT7 in PCa cell growth and androgen-induc...

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Detalles Bibliográficos
Autores principales: Ding, Mao, Jiang, Chen-Yi, Zhang, Yu, Zhao, Jing, Han, Bang-Min, Xia, Shu-Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6998106/
https://www.ncbi.nlm.nih.gov/pubmed/32019578
http://dx.doi.org/10.1186/s13046-019-1516-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6998106/
https://www.ncbi.nlm.nih.gov/pubmed/32019578
http://dx.doi.org/10.1186/s13046-019-1516-1

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