Metformin improves lipid metabolism and reverses the Warburg effect in a canine model of chronic atrial fibrillation

BACKGROUND: Previous studies demonstrated impaired lipid metabolism and augmented aerobic glycolysis in AF. The authors aimed to investigate whether the use of metformin, an AMPK activator, could reverse this metabolic remodeling in chronic AF and to explore the underlying mechanisms. METHODS: We co...

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Detalles Bibliográficos
Autores principales: Liu, Yaozhong, Bai, Fan, Liu, Na, Zhang, Baojian, Qin, Fen, Tu, Tao, Li, Biao, Li, Jiayi, Ma, Yingxu, Ouyang, Feifan, Liu, Qiming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6998172/
https://www.ncbi.nlm.nih.gov/pubmed/32013885
http://dx.doi.org/10.1186/s12872-020-01359-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6998172/
https://www.ncbi.nlm.nih.gov/pubmed/32013885
http://dx.doi.org/10.1186/s12872-020-01359-7

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