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Rapid generation of purified human RPE from pluripotent stem cells using 2D cultures and lipoprotein uptake-based sorting

BACKGROUND: Despite increasing demand, current protocols for human pluripotent stem cell (hPSC)-derived retinal pigment epithelium (RPE) remain time, labor, and cost intensive. Additionally, absence of robust methods for selective RPE purification and removal of non-RPE cell impurities prevents upsc...

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Detalles Bibliográficos
Autores principales:	Michelet, Fabio, Balasankar, Aishwarya, Teo, Nickolas, Stanton, Lawrence W., Singhal, Shweta
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6998340/ https://www.ncbi.nlm.nih.gov/pubmed/32014053 http://dx.doi.org/10.1186/s13287-020-1568-3

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