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AICAR and nicotinamide treatment synergistically augment the proliferation and attenuate senescence-associated changes in mesenchymal stromal cells

BACKGROUND: Mesenchymal stromal cell (MSC) stemness capacity diminishes over prolonged in vitro culture, which negatively affects their application in regenerative medicine. To slow down the senescence of MSCs, here, we have evaluated the in vitro effects of 5-aminoimidazole-4-carboxamide ribonucleo...

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Detalles Bibliográficos
Autores principales:	Khorraminejad-Shirazi, Mohammadhossein, Sani, Mahsa, Talaei-Khozani, Tahereh, Dorvash, Mohammadreza, Mirzaei, Malihe, Faghihi, Mohammad Ali, Monabati, Ahmad, Attar, Armin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6998366/ https://www.ncbi.nlm.nih.gov/pubmed/32014016 http://dx.doi.org/10.1186/s13287-020-1565-6

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