Loss of RDM1 enhances hepatocellular carcinoma progression via p53 and Ras/Raf/ERK pathways

Hepatocellular carcinoma (HCC), with its ineffective therapeutic options and poor prognosis, represents a global threat. In the present study, we show that RAD52 motif 1 (RDM1), a key regulator of DNA double‐strand break repair and recombination, is downregulated in HCC tissues and suppresses tumor...

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Detalles Bibliográficos
Autores principales: Chen, Shi‐Lu, Liu, Li‐Li, Wang, Chun‐Hua, Lu, Shi‐Xun, Yang, Xia, He, Yang‐Fan, Zhang, Chris Zhiyi, Yun, Jing‐Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6998392/
https://www.ncbi.nlm.nih.gov/pubmed/31670863
http://dx.doi.org/10.1002/1878-0261.12593

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6998392/
https://www.ncbi.nlm.nih.gov/pubmed/31670863
http://dx.doi.org/10.1002/1878-0261.12593

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