Cargando…
Statistical distributions commonly used in measurement uncertainty in laboratory medicine
Uncertainty is an inseparable part of all types of measurement. Recently, the International Organization for Standardization (ISO) released a new standard (ISO 20914) on how to calculate measurement uncertainty (MU) in laboratory medicine. This standard can be regarded as the beginning of a new era...
Autores principales: | , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Croatian Society of Medical Biochemistry and Laboratory Medicine
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6999182/ https://www.ncbi.nlm.nih.gov/pubmed/32063728 http://dx.doi.org/10.11613/BM.2020.010101 |
_version_ | 1783493937951932416 |
---|---|
author | Coskun, Abdurrahman Oosterhuis, Wytze P. |
author_facet | Coskun, Abdurrahman Oosterhuis, Wytze P. |
author_sort | Coskun, Abdurrahman |
collection | PubMed |
description | Uncertainty is an inseparable part of all types of measurement. Recently, the International Organization for Standardization (ISO) released a new standard (ISO 20914) on how to calculate measurement uncertainty (MU) in laboratory medicine. This standard can be regarded as the beginning of a new era in laboratory medicine. Measurement uncertainty comprises various components and is used to calculate the total uncertainty. All components must be expressed in standard deviation (SD) and then combined. However, the characteristics of these components are not the same; some are expressed as SD, while others are expressed as a ± b, such as the purity of the reagents. All non-SD variables must be transformed into SD, which requires a detailed knowledge of common statistical distributions used in the calculation of MU. Here, the main statistical distributions used in MU calculation are briefly summarized. |
format | Online Article Text |
id | pubmed-6999182 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Croatian Society of Medical Biochemistry and Laboratory Medicine |
record_format | MEDLINE/PubMed |
spelling | pubmed-69991822020-02-15 Statistical distributions commonly used in measurement uncertainty in laboratory medicine Coskun, Abdurrahman Oosterhuis, Wytze P. Biochem Med (Zagreb) Lessons in Biostatistics Uncertainty is an inseparable part of all types of measurement. Recently, the International Organization for Standardization (ISO) released a new standard (ISO 20914) on how to calculate measurement uncertainty (MU) in laboratory medicine. This standard can be regarded as the beginning of a new era in laboratory medicine. Measurement uncertainty comprises various components and is used to calculate the total uncertainty. All components must be expressed in standard deviation (SD) and then combined. However, the characteristics of these components are not the same; some are expressed as SD, while others are expressed as a ± b, such as the purity of the reagents. All non-SD variables must be transformed into SD, which requires a detailed knowledge of common statistical distributions used in the calculation of MU. Here, the main statistical distributions used in MU calculation are briefly summarized. Croatian Society of Medical Biochemistry and Laboratory Medicine 2020-02-15 2020-02-15 /pmc/articles/PMC6999182/ /pubmed/32063728 http://dx.doi.org/10.11613/BM.2020.010101 Text en Croatian Society of Medical Biochemistry and Laboratory Medicine. This is an Open Access article distributed under the terms of the Creative Commons Attribution (http://creativecommons.org/licenses/by/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Lessons in Biostatistics Coskun, Abdurrahman Oosterhuis, Wytze P. Statistical distributions commonly used in measurement uncertainty in laboratory medicine |
title | Statistical distributions commonly used in measurement uncertainty in laboratory medicine |
title_full | Statistical distributions commonly used in measurement uncertainty in laboratory medicine |
title_fullStr | Statistical distributions commonly used in measurement uncertainty in laboratory medicine |
title_full_unstemmed | Statistical distributions commonly used in measurement uncertainty in laboratory medicine |
title_short | Statistical distributions commonly used in measurement uncertainty in laboratory medicine |
title_sort | statistical distributions commonly used in measurement uncertainty in laboratory medicine |
topic | Lessons in Biostatistics |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6999182/ https://www.ncbi.nlm.nih.gov/pubmed/32063728 http://dx.doi.org/10.11613/BM.2020.010101 |
work_keys_str_mv | AT coskunabdurrahman statisticaldistributionscommonlyusedinmeasurementuncertaintyinlaboratorymedicine AT oosterhuiswytzep statisticaldistributionscommonlyusedinmeasurementuncertaintyinlaboratorymedicine |