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Fat Mass and Obesity-Associated (FTO) Stimulates Osteogenic Differentiation of C3H10T1/2 Cells by Inducing Mild Endoplasmic Reticulum Stress via a Positive Feedback Loop with p-AMPK

Fat mass and obesity-associated (FTO) gene helps to regulate energy homeostasis in mammals by controlling energy expenditure. In addition, FTO functions in the regulation of obesity and adipogenic differentiation; however, a role in osteogenic differentiation is unknown. This study investigated the...

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Detalles Bibliográficos
Autores principales: Son, Hyo-Eun, Min, Hyeon-Young, Kim, Eun-Jung, Jang, Won-Gu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Molecular and Cellular Biology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6999711/
https://www.ncbi.nlm.nih.gov/pubmed/31940720
http://dx.doi.org/10.14348/molcells.2019.0136