Cargando…

Antitumor Activity of Thermosensitive Hydrogels Packaging Gambogic Acid Nanoparticles and Tumor-Penetrating Peptide iRGD Against Gastric Cancer

INTRODUCTION: Gambogic acid (GA) is proved to have anti-tumor effects on gastric cancer. Due to poor solubility, non-specific biological distribution, toxicity to normal tissues and short half-life, it is hard to be applied into the clinic. To overcome these issues, we developed a thermosensitive an...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Dinghu, Chu, Yanhong, Qian, Hanqing, Qian, Lingyu, Shao, Jie, Xu, Qiuping, Yu, Lixia, Li, Rutian, Zhang, Quanan, Wu, Fenglei, Liu, Baorui, Liu, Qin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2020
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6999774/ https://www.ncbi.nlm.nih.gov/pubmed/32099362 http://dx.doi.org/10.2147/IJN.S231448

Ejemplares similares

Anti-EGFR-iRGD recombinant protein modified biomimetic nanoparticles loaded with gambogic acid to enhance targeting and antitumor ability in colorectal cancer treatment
por: Zhang, Zhen, et al.
Publicado: (2018)

Anti-EGFR-iRGD recombinant protein conjugated silk fibroin nanoparticles for enhanced tumor targeting and antitumor efficiency
por: Bian, Xinyu, et al.
Publicado: (2016)

Gambogic acid-loaded biomimetic nanoparticles in colorectal cancer treatment
por: Zhang, Zhen, et al.
Publicado: (2017)

Bifunctional iRGD-anti-CD3 enhances antitumor potency of T cells by facilitating tumor infiltration and T-cell activation
por: Zhou, Shujuan, et al.
Publicado: (2021)

iRGD synergizes with PD-1 knockout immunotherapy by enhancing lymphocyte infiltration in gastric cancer
por: Ding, Naiqing, et al.
Publicado: (2019)

Combination Therapy with iRGD-antiCD3 and PD-1 Blockade Enhances Antitumor Potency of Cord Blood-Derived T Cells
por: Zhu, Mei, et al.
Publicado: (2021)

Tumor-penetration and antitumor efficacy of cetuximab are enhanced by co-administered iRGD in a murine model of human NSCLC
por: Zhang, Yang, et al.
Publicado: (2016)

Superior Antitumor Efficacy of IFN-α2b-Incorporated Photo-Cross-Linked Hydrogels Combined with T Cell Transfer and Low-Dose Irradiation Against Gastric Cancer
por: Liu, Qin, et al.
Publicado: (2020)

iRGD Peptide as a Tumor-Penetrating Enhancer for Tumor-Targeted Drug Delivery
por: Kang, Sujin, et al.
Publicado: (2020)

sTRAIL-iRGD is a promising therapeutic agent for gastric cancer treatment
por: Huang, Ying, et al.
Publicado: (2017)

Co-administration of iRGD with peptide HPRP-A1 to improve anticancer activity and membrane penetrability
por: Hu, Cuihua, et al.
Publicado: (2018)

DR5-Selective TRAIL Variant DR5-B Functionalized with Tumor-Penetrating iRGD Peptide for Enhanced Antitumor Activity against Glioblastoma
por: Yagolovich, Anne V., et al.
Publicado: (2022)

Modification of erythrocytes by internalizing Arg-Gly-Asp (iRGD) in boosting the curative effect of radiotherapy for gastric carcinoma
por: Zhou, Chong, et al.
Publicado: (2022)

Gambogic acid regulates the migration and invasion of colorectal cancer via microRNA-21-mediated activation of phosphatase and tensin homolog
por: Gao, Guangyi, et al.
Publicado: (2018)

An iRGD peptide conjugated heparin nanocarrier for gastric cancer therapy
por: Ai, Shichao, et al.
Publicado: (2018)

Coupling Gd-DTPA with a bispecific, recombinant protein anti-EGFR-iRGD complex improves tumor targeting in MRI
por: XIN, XIAOYAN, et al.
Publicado: (2016)

An iRGD Based Strategy to Study Electrochemically the Species Inside a Cell
por: Ning, Limin, et al.
Publicado: (2012)

A Novel Strategy to Improve the Therapeutic Efficacy of Gemcitabine for Non-Small Cell Lung Cancer by the Tumor-Penetrating Peptide iRGD
por: Zhang, Qing, et al.
Publicado: (2015)

Enhanced Therapeutic Efficacy of iRGD-Conjugated Crosslinked Multilayer Liposomes for Drug Delivery
por: Liu, Yarong, et al.
Publicado: (2013)

Development of iRGD-Modified Peptide Carriers for Suicide Gene Therapy of Uterine Leiomyoma
por: Egorova, Anna, et al.
Publicado: (2021)

Dual Effect of Chemo-PDT with Tumor Targeting Nanoparticles Containing iRGD Peptide
por: Kim, Gye Lim, et al.
Publicado: (2023)

Anticancer activity of Pseudomonas aeruginosa derived peptide with iRGD in colon cancer therapy
por: Yaghoubi, Atieh, et al.
Publicado: (2023)

iRGD-Targeted Peptide Nanoparticles for Anti-Angiogenic RNAi-Based Therapy of Endometriosis
por: Egorova, Anna, et al.
Publicado: (2023)

MicroRNA-200c Nanoparticles Sensitized Gastric Cancer Cells to Radiotherapy by Regulating PD-L1 Expression and EMT
por: Qian, Lingyu, et al.
Publicado: (2020)

Synergistic anti-proliferative effects of gambogic acid with docetaxel in gastrointestinal cancer cell lines
por: Zou, Zhengyun, et al.
Publicado: (2012)

Antitumor effect of iRGD-modified liposomes containing conjugated linoleic acid–paclitaxel (CLA-PTX) on B16-F10 melanoma
por: Du, Ruo, et al.
Publicado: (2014)

Evaluation of anti-EGFR-iRGD recombinant protein with GOLD nanoparticles: synergistic effect on antitumor efficiency using optimized deep neural networks
por: Chandra Kaushik, Aman, et al.
Publicado: (2019)

Improved Anticancer Effect of Recombinant Protein izTRAIL Combined with Sorafenib and Peptide iRGD
por: Fadeev, Roman, et al.
Publicado: (2019)

Remarkable Boron Delivery Of iRGD-Modified Polymeric Nanoparticles For Boron Neutron Capture Therapy
por: Chen, Jiejian, et al.
Publicado: (2019)

Molecular Imaging of Steroid-Induced Osteonecrosis of the Femoral Head through iRGD-Targeted Microbubbles
por: Zhao, Ping, et al.
Publicado: (2022)

iRGD-modified memory-like NK cells exhibit potent responses to hepatocellular carcinoma
por: Dong, Yanbing, et al.
Publicado: (2023)

Molecular View on the iRGD Peptide Binding Mechanism: Implications for Integrin Activity and Selectivity Profiles
por: D’Amore, Vincenzo Maria, et al.
Publicado: (2023)

Effective Triple-Negative Breast Cancer Targeted Treatment Using iRGD-Modified RBC Membrane-Camouflaged Nanoparticles
por: Huang, Jingbin, et al.
Publicado: (2021)

In situ gelatinase-responsive and thermosensitive nanocomplex for local therapy of gastric cancer with peritoneal metastasis
por: Wang, Xinyue, et al.
Publicado: (2022)

iRGD: A Promising Peptide for Cancer Imaging and a Potential Therapeutic Agent for Various Cancers
por: Zuo, Houdong
Publicado: (2019)

iRGD conjugated nimbolide liposomes protect against endotoxin induced acute respiratory distress syndrome
por: Pooladanda, Venkatesh, et al.
Publicado: (2021)

Combined Self-Assembled iRGD Polymersomes for Effective Targeted siRNA Anti-Tumor Therapy
por: Li, Dongying, et al.
Publicado: (2022)

Correction: iRGD-modified memory-like NK cells exhibit potent responses to hepatocellular carcinoma
por: Dong, Yanbing, et al.
Publicado: (2023)

The Antitumour Activity of a Curcumin and Piperine Loaded iRGD-Modified Liposome: In Vitro and In Vivo Evaluation
por: Wang, Yingzheng, et al.
Publicado: (2023)

Novel silk fibroin nanoparticles incorporated silk fibroin hydrogel for inhibition of cancer stem cells and tumor growth
por: Wu, Puyuan, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_vbdtkshkl2c7fh2vrnr3u3ehee