Electrosprayed Polymeric Nanospheres for Enhanced Solubility, Dissolution Rate, Oral Bioavailability and Antihyperlipidemic Activity of Bezafibrate

BACKGROUND: Bezafibrate is a BCS class II drug as it presents very low solubility in water; therefore, its bioavailability after oral administration is very poor. The aim of this work was to enhance solubility and dissolution rate of bezafibrate in water in order to enhance its oral bioavailability....

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Detalles Bibliográficos
Autores principales: Sun, Ru, Shen, Chengwu, Shafique, Shumaila, Mustapha, Omer, Hussain, Talib, Khan, Ikram Ullah, Mehmood, Yasir, Anwer, Khaleeq, Shahzad, Yasser, Yousaf, Abid Mehmood
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6999775/
https://www.ncbi.nlm.nih.gov/pubmed/32099359
http://dx.doi.org/10.2147/IJN.S235146

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