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Peripheral Neuropathic Pain and Pain Related to Complex Regional Pain Syndrome with and without Fixed Dystonia – Efficient Therapeutic Approach with Local Anesthetics

Peripheral Neuropathic Pain (PNP) as well as the Complex Regional Pain Syndrome (CRPS), also known as “Reflex Sympathetic Dystrophy”, or “Sudeck Dystrophy”, all of them have a poor prognosis. The numerous therapeutic offers are rarely accompanied by convincing success over a long duration of time. E...

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Autor principal: Michels, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6999782/
https://www.ncbi.nlm.nih.gov/pubmed/32099453
http://dx.doi.org/10.2147/LRA.S229315
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author Michels, Thomas
author_facet Michels, Thomas
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description Peripheral Neuropathic Pain (PNP) as well as the Complex Regional Pain Syndrome (CRPS), also known as “Reflex Sympathetic Dystrophy”, or “Sudeck Dystrophy”, all of them have a poor prognosis. The numerous therapeutic offers are rarely accompanied by convincing success over a long duration of time. Even worse is the prognosis of a fixed dystonia which may develop in the extremities of PNP or CRPS patients. In literature a few cases are reported in which the often unbearable pain of those patients with or without a disabling dystonia disappeared immediately after the injection of local anesthetics (LAs) into the scars of a preceding trauma. This review evaluates publications concerning the neuropathological characteristics of fixed dystonia in PNP/CRPS patients and the electrophysiological processes of scar neuromas. The results of these evaluations support the understanding of the therapeutic successes and their immediate results reported above by the injection of LAs into triggering scars. Therapeutic options are discussed.
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spelling pubmed-69997822020-02-25 Peripheral Neuropathic Pain and Pain Related to Complex Regional Pain Syndrome with and without Fixed Dystonia – Efficient Therapeutic Approach with Local Anesthetics Michels, Thomas Local Reg Anesth Review Peripheral Neuropathic Pain (PNP) as well as the Complex Regional Pain Syndrome (CRPS), also known as “Reflex Sympathetic Dystrophy”, or “Sudeck Dystrophy”, all of them have a poor prognosis. The numerous therapeutic offers are rarely accompanied by convincing success over a long duration of time. Even worse is the prognosis of a fixed dystonia which may develop in the extremities of PNP or CRPS patients. In literature a few cases are reported in which the often unbearable pain of those patients with or without a disabling dystonia disappeared immediately after the injection of local anesthetics (LAs) into the scars of a preceding trauma. This review evaluates publications concerning the neuropathological characteristics of fixed dystonia in PNP/CRPS patients and the electrophysiological processes of scar neuromas. The results of these evaluations support the understanding of the therapeutic successes and their immediate results reported above by the injection of LAs into triggering scars. Therapeutic options are discussed. Dove 2020-01-31 /pmc/articles/PMC6999782/ /pubmed/32099453 http://dx.doi.org/10.2147/LRA.S229315 Text en © 2020 Michels. http://creativecommons.org/licenses/by-nc/3.0/ This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php).
spellingShingle Review
Michels, Thomas
Peripheral Neuropathic Pain and Pain Related to Complex Regional Pain Syndrome with and without Fixed Dystonia – Efficient Therapeutic Approach with Local Anesthetics
title Peripheral Neuropathic Pain and Pain Related to Complex Regional Pain Syndrome with and without Fixed Dystonia – Efficient Therapeutic Approach with Local Anesthetics
title_full Peripheral Neuropathic Pain and Pain Related to Complex Regional Pain Syndrome with and without Fixed Dystonia – Efficient Therapeutic Approach with Local Anesthetics
title_fullStr Peripheral Neuropathic Pain and Pain Related to Complex Regional Pain Syndrome with and without Fixed Dystonia – Efficient Therapeutic Approach with Local Anesthetics
title_full_unstemmed Peripheral Neuropathic Pain and Pain Related to Complex Regional Pain Syndrome with and without Fixed Dystonia – Efficient Therapeutic Approach with Local Anesthetics
title_short Peripheral Neuropathic Pain and Pain Related to Complex Regional Pain Syndrome with and without Fixed Dystonia – Efficient Therapeutic Approach with Local Anesthetics
title_sort peripheral neuropathic pain and pain related to complex regional pain syndrome with and without fixed dystonia – efficient therapeutic approach with local anesthetics
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6999782/
https://www.ncbi.nlm.nih.gov/pubmed/32099453
http://dx.doi.org/10.2147/LRA.S229315
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