Cargando…

The central regulator p62 between ubiquitin proteasome system and autophagy and its role in the mitophagy and Parkinson’s disease

The ubiquitin-proteasome system (UPS) and autophagy are two major degradative pathways of proteins in eukaryotic cells. As about 30% of newly synthesized proteins are known to be misfolded under normal cell conditions, the precise and timely operation of the UPS and autophagy to remove them as well...

Descripción completa

Detalles Bibliográficos
Autores principales:	Shin, Woo Hyun, Park, Joon Hyung, Chung, Kwang Chul
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Korean Society for Biochemistry and Molecular Biology 2020
Materias:	Invited Mini Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6999829/ https://www.ncbi.nlm.nih.gov/pubmed/31818366 http://dx.doi.org/10.5483/BMBRep.2020.53.1.283

Ejemplares similares

Precise control of mitophagy through ubiquitin proteasome system and deubiquitin proteases and their dysfunction in Parkinson’s disease
por: Park, Ga Hyun, et al.
Publicado: (2021)

p62 links the autophagy pathway and the ubiqutin–proteasome system upon ubiquitinated protein degradation
por: Liu, Wei Jing, et al.
Publicado: (2016)

Precise assembly and regulation of 26S proteasome and correlation between proteasome dysfunction and neurodegenerative diseases
por: Im, Eunju, et al.
Publicado: (2016)

p62 at the crossroad of the ubiquitin-proteasome system and autophagy
por: Cohen-Kaplan, Victoria, et al.
Publicado: (2016)

Emerging role of mitophagy in human diseases and physiology
por: Um, Jee-Hyun, et al.
Publicado: (2017)

Mitophagy: a balance regulator of NLRP3 inflammasome activation
por: Kim, Min-Ji, et al.
Publicado: (2016)

Ubiquitin-regulating effector proteins from Legionella
por: Jeong, Minwoo, et al.
Publicado: (2022)

Ubiquitin E3 ligases in cancer: somatic mutation and amplification
por: Jo, Eun-Hye, et al.
Publicado: (2023)

Regulation of polyubiquitin genes to meet cellular ubiquitin requirement
por: Han, Seung-Woo, et al.
Publicado: (2021)

P62 Links the Autophagy Pathway and the Ubiquitin–Proteasome System in Endothelial Cells during Atherosclerosis
por: Kim, SeJeong, et al.
Publicado: (2021)

Modulation of the ubiquitin-proteasome system by marine natural products
por: Vasilopoulou, Mary Α., et al.
Publicado: (2021)

Effects of mTORC1 inhibition on proteasome activity and levels
por: Park, Seo Hyeong, et al.
Publicado: (2022)

E3 ubiquitin ligases and deubiquitinases as modulators of TRAIL-mediated extrinsic apoptotic signaling pathway
por: Woo, Seon Min, et al.
Publicado: (2019)

New insight into transglutaminase 2 and link to neurodegenerative diseases
por: Min, Boram, et al.
Publicado: (2018)

Structure biology of selective autophagy receptors
por: Kim, Byeong-Won, et al.
Publicado: (2016)

Regulation of the Hippo signaling pathway by ubiquitin modification
por: Kim, Youngeun, et al.
Publicado: (2018)

Broad activation of the ubiquitin–proteasome system by Parkin is critical for mitophagy
por: Chan, Nickie C., et al.
Publicado: (2011)

The yeast mitophagy receptor Atg32 is ubiquitinated and degraded by the proteasome
por: Camougrand, Nadine, et al.
Publicado: (2020)

Variants of mitochondrial autophagy: Types 1 and 2 mitophagy and micromitophagy (Type 3)()
por: Lemasters, John J.
Publicado: (2014)

The ubiquitin proteasome system in synaptic and axonal degeneration: a new twist to an old cycle
por: Korhonen, Laura, et al.
Publicado: (2004)

The ubiquitin-proteasome system: A novel target for anticancer and anti-inflammatory drug research
por: Ostrowska, Halina
Publicado: (2008)

Sarcopenia targeting with autophagy mechanism by exercise
por: Park, Sung Sup, et al.
Publicado: (2019)

Therapeutic implication of autophagy in neurodegenerative diseases
por: Rahman, Md. Ataur, et al.
Publicado: (2017)

Role of the mammalian ATG8/LC3 family in autophagy: differential and compensatory roles in the spatiotemporal regulation of autophagy
por: Lee, You-Kyung, et al.
Publicado: (2016)

Role of post-translational modifications on the alpha-synuclein aggregation-related pathogenesis of Parkinson’s disease
por: Yoo, Hajung, et al.
Publicado: (2022)

CRISPR system for genome engineering: the application for autophagy study
por: Cui, Jianzhou, et al.
Publicado: (2017)

Quantitative and qualitative analysis of autophagy flux using imaging
por: Kim, Suree, et al.
Publicado: (2020)

LRRK2 and membrane trafficking: nexus of Parkinson’s disease
por: Hur, Eun-Mi, et al.
Publicado: (2019)

p62 filaments capture and present ubiquitinated cargos for autophagy
por: Zaffagnini, Gabriele, et al.
Publicado: (2018)

A mathematical model of p62-ubiquitin aggregates in autophagy
por: Delacour, Julia, et al.
Publicado: (2021)

The peripheral and central mechanisms underlying itch
por: Lee, Jae Seung, et al.
Publicado: (2016)

Emerging Paradigm of Crosstalk between Autophagy and the Ubiquitin-Proteasome System
por: Nam, Taewook, et al.
Publicado: (2017)

Role of the ubiquitin proteasome system in Parkinson's disease
por: Lim, Kah-Leong, et al.
Publicado: (2007)

Tollip negatively regulates mitophagy by promoting the mitochondrial processing and cytoplasmic release of PINK1
por: Shin, Woo Hyun, et al.
Publicado: (2022)

Interplay between the Ubiquitin Proteasome System and Ubiquitin-Mediated Autophagy in Plants
por: Su, Tong, et al.
Publicado: (2020)

Function and dysfunction of leucine-rich repeat kinase 2 (LRRK2): Parkinson’s disease and beyond
por: Bae, Jae Ryul, et al.
Publicado: (2015)

Untold story of human cervical cancers: HPV-negative cervical cancer
por: Lee, Jae-Eun, et al.
Publicado: (2022)

The Role of the Selective Adaptor p62 and Ubiquitin-Like Proteins in Autophagy
por: Lippai, Mónika, et al.
Publicado: (2014)

Odorant receptors in cancer
por: Chung, Chan, et al.
Publicado: (2022)

Patient-specific pluripotent stem cell-based Parkinson’s disease models showing endogenous alpha-synuclein aggregation
por: Oh, Yohan
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_0t2h1buahu1vdddjsuq6keedk5