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Mycobacterium tuberculosis thymidylate synthase (ThyX) is a target for plumbagin, a natural product with antimycobacterial activity

Plumbagin derived from the plant Plumbago indica, known as Chitrak in India, is an example of a medicinal compound used traditionally to cure a variety of ailments. Previous reports have indicated that it can inhibit the growth of Mycobacterium tuberculosis (Mtb), the causative agent of the deadly d...

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Detalles Bibliográficos
Autores principales: Sarkar, Apurba, Ghosh, Shreya, Shaw, Rahul, Patra, Madhu Manti, Calcuttawala, Fatema, Mukherjee, Noyonika, Das Gupta, Sujoy K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6999906/
https://www.ncbi.nlm.nih.gov/pubmed/32017790
http://dx.doi.org/10.1371/journal.pone.0228657