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Muscle stem cell renewal suppressed by Gas1 can be reversed by GDNF in mice
Muscle undergoes progressive weakening and regenerative dysfunction with age due in part to the functional decline of skeletal muscle stem cells (MuSCs). MuSCs are heterogeneous but whether their gene expression changes with age and the implication of such changes are unclear. Here we show that in m...
Autores principales: | Li, Liangji, Rozo, Michelle, Yue, Sibiao, Zheng, Xiaobin, Tan, Frederick, Lepper, Christoph, Fan, Chen-Ming |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7000153/ https://www.ncbi.nlm.nih.gov/pubmed/32021964 http://dx.doi.org/10.1038/s42255-019-0110-3 |
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