A Fyn biosensor reveals pulsatile, spatially localized kinase activity and signaling crosstalk in live mammalian cells

Cell behavior is controlled through spatio-temporally localized protein activity. Despite unique and often contradictory roles played by Src-family-kinases (SFKs) in regulating cell physiology, activity patterns of individual SFKs have remained elusive. Here, we report a biosensor for specifically v...

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Detalles Bibliográficos
Autores principales: Mukherjee, Ananya, Singh, Randhir, Udayan, Sreeram, Biswas, Sayan, Reddy, Pothula Purushotham, Manmadhan, Saumya, George, Geen, Kumar, Shilpa, Das, Ranabir, Rao, Balaji M, Gulyani, Akash
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Biochemistry and Chemical Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7000222/
https://www.ncbi.nlm.nih.gov/pubmed/32017701
http://dx.doi.org/10.7554/eLife.50571

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