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Oncogene-dependent function of BRG1 in hepatocarcinogenesis

Hepatocellular carcinoma (HCC) is the major type of primary liver cancer. Genomic studies have revealed that HCC is a heterogeneous disease with multiple subtypes. BRG1, encoded by the SMARCA4 gene, is a key component of SWI/SNF chromatin-remodeling complexes. Based on TCGA studies, somatic mutation...

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Detalles Bibliográficos
Autores principales:	Wang, Pan, Song, Xinhua, Cao, Dan, Cui, Kairong, Wang, Jingxiao, Utpatel, Kirsten, Shang, Runze, Wang, Haichuan, Che, Li, Evert, Matthias, Zhao, Keji, Calvisi, Diego F., Chen, Xin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7000409/ https://www.ncbi.nlm.nih.gov/pubmed/32019910 http://dx.doi.org/10.1038/s41419-020-2289-3

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