Factor VIII Fc Fusion Protein but not FVIII Drives Human Monocyte-Derived Dendritic Cell Activation via FcγRIIa

This study compares the effect of recombinant Factor VIII Fc fusion protein (rFVIII-Fc) with recombinant FVIII (rFVIII) on monocyte-derived dendritic cells (moDC's). Cells treated with rFVIII-Fc showed morphological changes typical for cell activation, had a significant up-regulation of cell ac...

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Detalles Bibliográficos
Autores principales: Kannicht, Christoph, Danßmann, Ilona, Weilandt, Constanze, Derkow, Katja, Kohla, Guido, Geyer, Henriette
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7000470/
https://www.ncbi.nlm.nih.gov/pubmed/32072146
http://dx.doi.org/10.1097/HS9.0000000000000330

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7000470/
https://www.ncbi.nlm.nih.gov/pubmed/32072146
http://dx.doi.org/10.1097/HS9.0000000000000330

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