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Factor VIII Fc Fusion Protein but not FVIII Drives Human Monocyte-Derived Dendritic Cell Activation via FcγRIIa

This study compares the effect of recombinant Factor VIII Fc fusion protein (rFVIII-Fc) with recombinant FVIII (rFVIII) on monocyte-derived dendritic cells (moDC's). Cells treated with rFVIII-Fc showed morphological changes typical for cell activation, had a significant up-regulation of cell ac...

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Detalles Bibliográficos
Autores principales:	Kannicht, Christoph, Danßmann, Ilona, Weilandt, Constanze, Derkow, Katja, Kohla, Guido, Geyer, Henriette
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Wolters Kluwer Health 2020
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7000470/ https://www.ncbi.nlm.nih.gov/pubmed/32072146 http://dx.doi.org/10.1097/HS9.0000000000000330

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