TAM-ing T cells in the tumor microenvironment: implications for TAM receptor targeting

The TAM receptors—TYRO3, AXL, MERTK—are pleiotropically expressed receptors in both healthy and diseased tissue. A complex of the ligands Protein S (PROS1) or Growth Arrest-Specific 6 (GAS6) with apoptotic phosphatidylserine activates the TAM receptors. Hence, this receptor family is essential for t...

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Detalles Bibliográficos
Autores principales: Peeters, Marlies J. W., Rahbech, Anne, thor Straten, Per
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2019
Materias:
Focussed Research Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7000491/
https://www.ncbi.nlm.nih.gov/pubmed/31664482
http://dx.doi.org/10.1007/s00262-019-02421-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7000491/
https://www.ncbi.nlm.nih.gov/pubmed/31664482
http://dx.doi.org/10.1007/s00262-019-02421-w

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