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A prospective analysis of robotic targeted MRI-US fusion prostate biopsy using the centroid targeting approach

Robotic prostate biopsy is an emerging technology. Recent development of this tool has allowed the performance of a transperineal prostate biopsy allowing pre-programmed standardized biopsy schemes. Prospective data collection was undertaken in 86 consecutive men who underwent robotically assisted t...

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Autores principales: Miah, Saiful, Servian, Pol, Patel, Amit, Lovegrove, Catherine, Skelton, Lindsey, Shah, Taimur T., Eldred-Evans, David, Arya, Manit, Tam, Henry, Ahmed, Hashim U., Winkler, Mathias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer London 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7000504/
https://www.ncbi.nlm.nih.gov/pubmed/30783886
http://dx.doi.org/10.1007/s11701-019-00929-y
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author Miah, Saiful
Servian, Pol
Patel, Amit
Lovegrove, Catherine
Skelton, Lindsey
Shah, Taimur T.
Eldred-Evans, David
Arya, Manit
Tam, Henry
Ahmed, Hashim U.
Winkler, Mathias
author_facet Miah, Saiful
Servian, Pol
Patel, Amit
Lovegrove, Catherine
Skelton, Lindsey
Shah, Taimur T.
Eldred-Evans, David
Arya, Manit
Tam, Henry
Ahmed, Hashim U.
Winkler, Mathias
author_sort Miah, Saiful
collection PubMed
description Robotic prostate biopsy is an emerging technology. Recent development of this tool has allowed the performance of a transperineal prostate biopsy allowing pre-programmed standardized biopsy schemes. Prospective data collection was undertaken in 86 consecutive men who underwent robotically assisted transperineal prostate biopsy. All underwent a multi-parametric MRI pre-biopsy with centroid targeting followed by systematic template prostate biopsy. For the purposes of this study, our definition of clinically significant prostate cancer (csPCa) is any Gleason score > 6. Mean (SD) age, median (IQR) PSA, and median (IQR) prostate volume were 64.24 (6.97) years, of 7.79 ng/ml (6.5) and 45.06 cc (28), respectively. Overall, 44 (51.2%) men were diagnosed with csPCa. csPCa was detected in the targeted biopsies alone in 35 (40.1%) men. The addition of the 12-zone template biopsy increased the yield of csPCa for another 9 (10.5%) men. Of these 9 men, the majority (7) harbored primary pattern 3 disease and only 1 was identified to have high-grade disease. Out of these 9 men, 7 of them had the identification of csPCa in the sector, where a target was contained within that zone. Robotic-assisted prostate biopsy in our study has demonstrated a high detection of csPCa when combined with limited near-field sampling. Our study suggests the use of more accurate biopsy schemes such as ring-targeting of lesions to mitigate against systematic and random mathematical errors. Adoption of this tool and biopsy strategy would potentially avoid the increased morbidity associated with whole gland systematic unguided biopsies.
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spelling pubmed-70005042020-02-21 A prospective analysis of robotic targeted MRI-US fusion prostate biopsy using the centroid targeting approach Miah, Saiful Servian, Pol Patel, Amit Lovegrove, Catherine Skelton, Lindsey Shah, Taimur T. Eldred-Evans, David Arya, Manit Tam, Henry Ahmed, Hashim U. Winkler, Mathias J Robot Surg Original Article Robotic prostate biopsy is an emerging technology. Recent development of this tool has allowed the performance of a transperineal prostate biopsy allowing pre-programmed standardized biopsy schemes. Prospective data collection was undertaken in 86 consecutive men who underwent robotically assisted transperineal prostate biopsy. All underwent a multi-parametric MRI pre-biopsy with centroid targeting followed by systematic template prostate biopsy. For the purposes of this study, our definition of clinically significant prostate cancer (csPCa) is any Gleason score > 6. Mean (SD) age, median (IQR) PSA, and median (IQR) prostate volume were 64.24 (6.97) years, of 7.79 ng/ml (6.5) and 45.06 cc (28), respectively. Overall, 44 (51.2%) men were diagnosed with csPCa. csPCa was detected in the targeted biopsies alone in 35 (40.1%) men. The addition of the 12-zone template biopsy increased the yield of csPCa for another 9 (10.5%) men. Of these 9 men, the majority (7) harbored primary pattern 3 disease and only 1 was identified to have high-grade disease. Out of these 9 men, 7 of them had the identification of csPCa in the sector, where a target was contained within that zone. Robotic-assisted prostate biopsy in our study has demonstrated a high detection of csPCa when combined with limited near-field sampling. Our study suggests the use of more accurate biopsy schemes such as ring-targeting of lesions to mitigate against systematic and random mathematical errors. Adoption of this tool and biopsy strategy would potentially avoid the increased morbidity associated with whole gland systematic unguided biopsies. Springer London 2019-02-19 2020 /pmc/articles/PMC7000504/ /pubmed/30783886 http://dx.doi.org/10.1007/s11701-019-00929-y Text en © The Author(s) 2019 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.
spellingShingle Original Article
Miah, Saiful
Servian, Pol
Patel, Amit
Lovegrove, Catherine
Skelton, Lindsey
Shah, Taimur T.
Eldred-Evans, David
Arya, Manit
Tam, Henry
Ahmed, Hashim U.
Winkler, Mathias
A prospective analysis of robotic targeted MRI-US fusion prostate biopsy using the centroid targeting approach
title A prospective analysis of robotic targeted MRI-US fusion prostate biopsy using the centroid targeting approach
title_full A prospective analysis of robotic targeted MRI-US fusion prostate biopsy using the centroid targeting approach
title_fullStr A prospective analysis of robotic targeted MRI-US fusion prostate biopsy using the centroid targeting approach
title_full_unstemmed A prospective analysis of robotic targeted MRI-US fusion prostate biopsy using the centroid targeting approach
title_short A prospective analysis of robotic targeted MRI-US fusion prostate biopsy using the centroid targeting approach
title_sort prospective analysis of robotic targeted mri-us fusion prostate biopsy using the centroid targeting approach
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7000504/
https://www.ncbi.nlm.nih.gov/pubmed/30783886
http://dx.doi.org/10.1007/s11701-019-00929-y
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