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HMGB1 Protects the Heart Against Ischemia–Reperfusion Injury via PI3K/AkT Pathway-Mediated Upregulation of VEGF Expression

Delivery of exogenous high mobility group box 1 (HMGB1) may exert a beneficial effect on myocardial ischemia–reperfusion (I/R) injury. Since the expression of vascular endothelial growth factor (VEGF) and phosphatidylinositol 3-kinase/protein kinase B (PI3K/Akt) in the myocardium mediates the cardio...

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Detalles Bibliográficos
Autores principales:	Zhou, Yan-Hong, Han, Qian-Feng, Gao, Lei, Sun, Ying, Tang, Zhan-Wei, Wang, Meng, Wang, Wei, Yao, Heng-Chen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Physiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7000523/ https://www.ncbi.nlm.nih.gov/pubmed/32063860 http://dx.doi.org/10.3389/fphys.2019.01595

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