Pharmacometabolomics Identifies 3-Hydroxyadipic Acid, d-Galactose, Lysophosphatidylcholine (P-16:0), and Tetradecenoyl-l-Carnitine as Potential Predictive Indicators of Gemcitabine Efficacy in Pancreatic Cancer Patients

Gemcitabine (GEM)-based chemotherapy is the standard regimen for the treatment of pancreatic cancer (PC). However, chemoresistance is a major challenge in PC treatment. Reliable biomarkers are urgently needed to predict the response to GEM-based therapies. GEM-sensitive (GEM-S) and GEM-resistant (GE...

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Detalles Bibliográficos
Autores principales: Wu, Dongyuan, Li, Xinyuan, Zhang, Xiaohan, Han, Fang, Lu, Xin, Liu, Lei, Zhang, Junsheng, Dong, Mei, Yang, Huanjie, Li, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7000527/
https://www.ncbi.nlm.nih.gov/pubmed/32064236
http://dx.doi.org/10.3389/fonc.2019.01524

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