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A Role of Cholesterol in Modulating the Binding of α-Synuclein to Synaptic-Like Vesicles
α-Synuclein (αS) is a presynaptic protein whose aggregation is associated with Parkinson’s disease (PD). Although the physiological function of αS is still unclear, several lines of evidence indicate that this protein may play a role in the trafficking of synaptic vesicles (SVs) during neurotransmit...
Autores principales: | Man, Wing K., De Simone, Alfonso, Barritt, Joseph D., Vendruscolo, Michele, Dobson, Christopher M., Fusco, Giuliana |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7000551/ https://www.ncbi.nlm.nih.gov/pubmed/32063829 http://dx.doi.org/10.3389/fnins.2020.00018 |
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