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A Role of Cholesterol in Modulating the Binding of α-Synuclein to Synaptic-Like Vesicles

α-Synuclein (αS) is a presynaptic protein whose aggregation is associated with Parkinson’s disease (PD). Although the physiological function of αS is still unclear, several lines of evidence indicate that this protein may play a role in the trafficking of synaptic vesicles (SVs) during neurotransmit...

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Detalles Bibliográficos
Autores principales: Man, Wing K., De Simone, Alfonso, Barritt, Joseph D., Vendruscolo, Michele, Dobson, Christopher M., Fusco, Giuliana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7000551/
https://www.ncbi.nlm.nih.gov/pubmed/32063829
http://dx.doi.org/10.3389/fnins.2020.00018

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