Anti-MAdCAM-1 antibody (PF-00547659) for active refractory Crohn’s disease in Japanese and Korean patients: the OPERA study

BACKGROUND/AIMS: PF-00547659 is a monoclonal antibody against human mucosal addressin cell adhesion molecule-1 (MAdCAM-1) that prevents the binding of α4β7(+) lymphocytes to MAdCAM-expressing sites in the gastrointestinal tract with high affinity and selectivity, and is being developed for the treat...

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Detalles Bibliográficos
Autores principales: Saruta, Masayuki, Park, Dong Il, Kim, Young-Ho, Yang, Suk-Kyun, Jang, Byung-Ik, Cheon, Jae Hee, Im, Jong Pil, Kanai, Takanori, Katsuno, Tatsuro, Ishiguro, Yoh, Nagaoka, Makoto, Isogawa, Naoki, Li, Yinhua, Banerjee, Anindita, Ahmad, Alaa, Hassan-Zahraee, Mina, Clare, Robert, Gorelick, Kenneth J., Cataldi, Fabio, Watanabe, Mamoru, Hibi, Toshifumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Association for the Study of Intestinal Diseases 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7000638/
https://www.ncbi.nlm.nih.gov/pubmed/32013314
http://dx.doi.org/10.5217/ir.2019.00039

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