Toxicology of paraquat and pharmacology of the protective effect of 5-hydroxy-1-methylhydantoin on lung injury caused by paraquat based on metabolomics

Paraquat (PQ) is a non-selective herbicide and is exceedingly toxic to humans. The mechanism of PQ toxicity is very complex and has not been clearly defined. There is no specific antidote for PQ poisoning. 5-hydroxy-1-methylhydantoin (HMH) is an intrinsic antioxidant and can protect against renal da...

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Detalles Bibliográficos
Autores principales: Gao, Lina, Yuan, Huiya, Xu, Enyu, Liu, Junting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7000692/
https://www.ncbi.nlm.nih.gov/pubmed/32019966
http://dx.doi.org/10.1038/s41598-020-58599-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7000692/
https://www.ncbi.nlm.nih.gov/pubmed/32019966
http://dx.doi.org/10.1038/s41598-020-58599-y

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