Altered platelet proteome in lupus anticoagulant (LA)-positive patients—protein disulfide isomerase and NETosis as new players in LA-related thrombosis

Patients with antiphospholipid syndrome (APS) are at high risk of developing venous and arterial thromboembolism (TE). The role of platelets in the pathogenesis of these prothrombotic conditions is not yet fully understood. The aim of this study was to gain mechanistic insights into the role of plat...

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Detalles Bibliográficos
Autores principales: Hell, Lena, Lurger, Kristina, Mauracher, Lisa-Marie, Grilz, Ella, Reumiller, Christina Maria, Schmidt, Georg Johannes, Ercan, Huriye, Koder, Silvia, Assinger, Alice, Basilio, José, Gebhart, Johanna, Ay, Cihan, Pabinger, Ingrid, Zellner, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7000701/
https://www.ncbi.nlm.nih.gov/pubmed/31956273
http://dx.doi.org/10.1038/s12276-019-0358-4

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