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Engaging chromatin: PRC2 structure meets function
Polycomb repressive complex 2 (PRC2) is a key epigenetic multiprotein complex involved in the regulation of gene expression in metazoans. PRC2 is formed by a tetrameric core that endows the complex with histone methyltransferase activity, allowing it to mono-, di- and tri-methylate histone H3 on lys...
Autores principales: | Chammas, Paul, Mocavini, Ivano, Di Croce, Luciano |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7000746/ https://www.ncbi.nlm.nih.gov/pubmed/31708574 http://dx.doi.org/10.1038/s41416-019-0615-2 |
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