Sustained treatment of retinal vascular diseases with self-aggregating sunitinib microparticles

Neovascular age-related macular degeneration and diabetic retinopathy are prevalent causes of vision loss requiring frequent intravitreous injections of VEGF-neutralizing proteins, and under-treatment is common and problematic. Here we report incorporation of sunitinib, a tyrosine kinase inhibitor t...

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Detalles Bibliográficos
Autores principales: Tsujinaka, Hiroki, Fu, Jie, Shen, Jikui, Yu, Yun, Hafiz, Zibran, Kays, Joshua, McKenzie, David, Cardona, Delia, Culp, David, Peterson, Ward, Gilger, Brian C., Crean, Christopher S., Zhang, Jin-Zhong, Kanan, Yogita, Yu, Weiling, Cleland, Jeffrey L., Yang, Ming, Hanes, Justin, Campochiaro, Peter A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7000758/
https://www.ncbi.nlm.nih.gov/pubmed/32019921
http://dx.doi.org/10.1038/s41467-020-14340-x

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