The iron load of lipocalin-2 (LCN-2) defines its pro-tumour function in clear-cell renal cell carcinoma

BACKGROUND: We aimed at clarifying the role of lipocalin-2 (LCN-2) in clear-cell renal cell carcinoma (ccRCC). Since LCN-2 was recently identified as a novel iron transporter, we explored its iron load as a decisive factor in conferring its biological function. METHODS: LCN-2 expression was analysed...

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Detalles Bibliográficos
Autores principales: Rehwald, Claudia, Schnetz, Matthias, Urbschat, Anja, Mertens, Christina, Meier, Julia K., Bauer, Rebekka, Baer, Patrick, Winslow, Sofia, Roos, Frederik C., Zwicker, Klaus, Huard, Arnaud, Weigert, Andreas, Brüne, Bernhard, Jung, Michaela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7000824/
https://www.ncbi.nlm.nih.gov/pubmed/31772326
http://dx.doi.org/10.1038/s41416-019-0655-7

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