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Impaired Delivery of Cholesterol Effluxed From Macrophages to Hepatocytes by Serum From CKD Patients May Underlie Increased Cardiovascular Disease Risk

INTRODUCTION: Although chronic kidney disease (CKD) is associated with increased risk for coronary artery disease (CAD), the underlying mechanisms are not completely defined. In the present study, we tested the hypothesis that flux of cholesterol from macrophage foam cells to liver is impaired in su...

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Detalles Bibliográficos
Autores principales: Gipson, Graham T., Carbone, Salvatore, Wang, Jing, Dixon, Dave L., Jovin, Ion S., Carl, Daniel E., Gehr, Todd W., Ghosh, Shobha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7000844/
https://www.ncbi.nlm.nih.gov/pubmed/32043034
http://dx.doi.org/10.1016/j.ekir.2019.11.003