Assessment of hemagglutination activity of porcine deltacoronavirus

Porcine deltacoronavirus (PDCoV) is an emerging swine enteric coronavirus that causes diarrhea in piglets. However, the biological characteristics of PDCoV are unclear. In this study, the hemagglutination (HA) abilities of two PDCoV strains (CH-01 and HNZK-04) were investigated. Our results showed t...

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Detalles Bibliográficos
Autores principales: Zhang, Yunfei, Han, Li, Xia, Lu, Yuan, Yixin, Hu, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Veterinary Science 2020
Materias:
Rapid Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7000906/
https://www.ncbi.nlm.nih.gov/pubmed/31940691
http://dx.doi.org/10.4142/jvs.2020.21.e12
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author Zhang, Yunfei
Han, Li
Xia, Lu
Yuan, Yixin
Hu, Hui
author_facet Zhang, Yunfei
Han, Li
Xia, Lu
Yuan, Yixin
Hu, Hui
author_sort Zhang, Yunfei
collection PubMed
description Porcine deltacoronavirus (PDCoV) is an emerging swine enteric coronavirus that causes diarrhea in piglets. However, the biological characteristics of PDCoV are unclear. In this study, the hemagglutination (HA) abilities of two PDCoV strains (CH-01 and HNZK-04) were investigated. Our results showed that PDCoV has the ability to agglutinate rabbit erythrocytes after virion pretreatment with trypsin or neuraminidase. Additionally, the HA assay results showed a significant positive correlation with the infectious viral titer. Our results suggest that assessing the HA activity of PDCoV may be a useful diagnostic method for investigating and surveilling PDCoV infections.
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spelling pubmed-70009062020-02-12 Assessment of hemagglutination activity of porcine deltacoronavirus Zhang, Yunfei Han, Li Xia, Lu Yuan, Yixin Hu, Hui J Vet Sci Rapid Communication Porcine deltacoronavirus (PDCoV) is an emerging swine enteric coronavirus that causes diarrhea in piglets. However, the biological characteristics of PDCoV are unclear. In this study, the hemagglutination (HA) abilities of two PDCoV strains (CH-01 and HNZK-04) were investigated. Our results showed that PDCoV has the ability to agglutinate rabbit erythrocytes after virion pretreatment with trypsin or neuraminidase. Additionally, the HA assay results showed a significant positive correlation with the infectious viral titer. Our results suggest that assessing the HA activity of PDCoV may be a useful diagnostic method for investigating and surveilling PDCoV infections. The Korean Society of Veterinary Science 2020-01 2019-12-13 /pmc/articles/PMC7000906/ /pubmed/31940691 http://dx.doi.org/10.4142/jvs.2020.21.e12 Text en © 2020 The Korean Society of Veterinary Science https://creativecommons.org/licenses/by-nc/4.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (https://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Rapid Communication
Zhang, Yunfei
Han, Li
Xia, Lu
Yuan, Yixin
Hu, Hui
Assessment of hemagglutination activity of porcine deltacoronavirus
title Assessment of hemagglutination activity of porcine deltacoronavirus
title_full Assessment of hemagglutination activity of porcine deltacoronavirus
title_fullStr Assessment of hemagglutination activity of porcine deltacoronavirus
title_full_unstemmed Assessment of hemagglutination activity of porcine deltacoronavirus
title_short Assessment of hemagglutination activity of porcine deltacoronavirus
title_sort assessment of hemagglutination activity of porcine deltacoronavirus
topic Rapid Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7000906/
https://www.ncbi.nlm.nih.gov/pubmed/31940691
http://dx.doi.org/10.4142/jvs.2020.21.e12
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