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TRPS1 acts as a context-dependent regulator of mammary epithelial cell growth/differentiation and breast cancer development

The GATA-type zinc finger transcription factor TRPS1 has been implicated in breast cancer. However, its precise role remains unclear, as both amplifications and inactivating mutations in TRPS1 have been reported. Here, we used in vitro and in vivo loss-of-function approaches to dissect the role of T...

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Detalles Bibliográficos
Autores principales: Cornelissen, Lisette M., Drenth, Anne Paulien, van der Burg, Eline, de Bruijn, Roebi, Pritchard, Colin E.J., Huijbers, Ivo J., Zwart, Wilbert, Jonkers, Jos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7000918/
https://www.ncbi.nlm.nih.gov/pubmed/31879358
http://dx.doi.org/10.1101/gad.331371.119