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TRPS1 acts as a context-dependent regulator of mammary epithelial cell growth/differentiation and breast cancer development
The GATA-type zinc finger transcription factor TRPS1 has been implicated in breast cancer. However, its precise role remains unclear, as both amplifications and inactivating mutations in TRPS1 have been reported. Here, we used in vitro and in vivo loss-of-function approaches to dissect the role of T...
Autores principales: | Cornelissen, Lisette M., Drenth, Anne Paulien, van der Burg, Eline, de Bruijn, Roebi, Pritchard, Colin E.J., Huijbers, Ivo J., Zwart, Wilbert, Jonkers, Jos |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7000918/ https://www.ncbi.nlm.nih.gov/pubmed/31879358 http://dx.doi.org/10.1101/gad.331371.119 |
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