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Cervicogenic exophthalmos: Possible etiology and pathogenesis

BACKGROUND: Unilateral exophthalmos is often caused by inflammation, neoplasm, infection, metabolic disease, vascular disorder and several other less common conditions. Reflex sympathetic dystrophy related to unilateral exophthalmos has not been reported in the past literature. CASE SUMMARY: We desc...

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Autores principales: Wu, Chi-Ming, Liao, Hung-En, Hsu, Shang-Wei, Lan, Shou-Jen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7000940/
https://www.ncbi.nlm.nih.gov/pubmed/32047780
http://dx.doi.org/10.12998/wjcc.v8.i2.318
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author Wu, Chi-Ming
Liao, Hung-En
Hsu, Shang-Wei
Lan, Shou-Jen
author_facet Wu, Chi-Ming
Liao, Hung-En
Hsu, Shang-Wei
Lan, Shou-Jen
author_sort Wu, Chi-Ming
collection PubMed
description BACKGROUND: Unilateral exophthalmos is often caused by inflammation, neoplasm, infection, metabolic disease, vascular disorder and several other less common conditions. Reflex sympathetic dystrophy related to unilateral exophthalmos has not been reported in the past literature. CASE SUMMARY: We describe a 45-year-old female with unilateral exophthalmos caused by reflex sympathetic dystrophy and its unexpected spontaneous disappearance after a standard anterior cervical discectomy and fixation operation with two PEEK interbody cages and a plate. To our surprise, the patient’s left unilateral exophthalmos improved spontaneously in the morning on postoperative day 2-with no relapse, without any further medication, as of seven years. We have named this condition “cervicogenic exophthalmos.” CONCLUSION: We would inform other clinicians that unilateral exophthalmos was caused not only by inflammation, vascular disorder, infection, neoplasm, or metabolic disease, but also by reflex sympathetic dystrophy related with cervicogenic spondylosis. To the best of our knowledge, ours is the first related case report and use of the term “cervicogenic exophthalmos” after reviewing previous literature.
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spelling pubmed-70009402020-02-11 Cervicogenic exophthalmos: Possible etiology and pathogenesis Wu, Chi-Ming Liao, Hung-En Hsu, Shang-Wei Lan, Shou-Jen World J Clin Cases Case Report BACKGROUND: Unilateral exophthalmos is often caused by inflammation, neoplasm, infection, metabolic disease, vascular disorder and several other less common conditions. Reflex sympathetic dystrophy related to unilateral exophthalmos has not been reported in the past literature. CASE SUMMARY: We describe a 45-year-old female with unilateral exophthalmos caused by reflex sympathetic dystrophy and its unexpected spontaneous disappearance after a standard anterior cervical discectomy and fixation operation with two PEEK interbody cages and a plate. To our surprise, the patient’s left unilateral exophthalmos improved spontaneously in the morning on postoperative day 2-with no relapse, without any further medication, as of seven years. We have named this condition “cervicogenic exophthalmos.” CONCLUSION: We would inform other clinicians that unilateral exophthalmos was caused not only by inflammation, vascular disorder, infection, neoplasm, or metabolic disease, but also by reflex sympathetic dystrophy related with cervicogenic spondylosis. To the best of our knowledge, ours is the first related case report and use of the term “cervicogenic exophthalmos” after reviewing previous literature. Baishideng Publishing Group Inc 2020-01-26 2020-01-26 /pmc/articles/PMC7000940/ /pubmed/32047780 http://dx.doi.org/10.12998/wjcc.v8.i2.318 Text en ©The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved. http://creativecommons.org/licenses/by-nc/4.0/ This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial.
spellingShingle Case Report
Wu, Chi-Ming
Liao, Hung-En
Hsu, Shang-Wei
Lan, Shou-Jen
Cervicogenic exophthalmos: Possible etiology and pathogenesis
title Cervicogenic exophthalmos: Possible etiology and pathogenesis
title_full Cervicogenic exophthalmos: Possible etiology and pathogenesis
title_fullStr Cervicogenic exophthalmos: Possible etiology and pathogenesis
title_full_unstemmed Cervicogenic exophthalmos: Possible etiology and pathogenesis
title_short Cervicogenic exophthalmos: Possible etiology and pathogenesis
title_sort cervicogenic exophthalmos: possible etiology and pathogenesis
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7000940/
https://www.ncbi.nlm.nih.gov/pubmed/32047780
http://dx.doi.org/10.12998/wjcc.v8.i2.318
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