Eye metastasis in lung adenocarcinoma mimicking anterior scleritis: A case report

BACKGROUND: The eye is a rare site for lung cancer metastasis. Indeed, ocular metastasis is one of the greatest challenges to quality of life in a cancer patient. Here we present a patient with lung adenocarcinoma and ocular metastasis. CASE SUMMARY: The patient was a 70-year-old man diagnosed with...

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Autores principales: Chen, Hua-Fei, Wang, Wen-Xian, Li, Xiao-Feng, Wu, Li-Xin, Zhu, You-Cai, Du, Kai-Qi, Xu, Chun-Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2020
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7000956/
https://www.ncbi.nlm.nih.gov/pubmed/32047793
http://dx.doi.org/10.12998/wjcc.v8.i2.410
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author Chen, Hua-Fei
Wang, Wen-Xian
Li, Xiao-Feng
Wu, Li-Xin
Zhu, You-Cai
Du, Kai-Qi
Xu, Chun-Wei
author_facet Chen, Hua-Fei
Wang, Wen-Xian
Li, Xiao-Feng
Wu, Li-Xin
Zhu, You-Cai
Du, Kai-Qi
Xu, Chun-Wei
author_sort Chen, Hua-Fei
collection PubMed
description BACKGROUND: The eye is a rare site for lung cancer metastasis. Indeed, ocular metastasis is one of the greatest challenges to quality of life in a cancer patient. Here we present a patient with lung adenocarcinoma and ocular metastasis. CASE SUMMARY: The patient was a 70-year-old man diagnosed with lung adenocarcinoma who developed eye metastasis mimicking anterior scleritis. Brain magnetic resonance imaging showed an abnormal signal in the right eye. Based on next generation sequencing of the surgical specimen, the patient was shown to have a KRAS point mutation (p.G12D). CONCLUSION: Multidiscipline expertise collaboration is needed to make the early diagnosis and determine the prompt treatment in patients. We hope to increase the awareness of the possibility of lung cancer metastasizing to the eye.
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spelling pubmed-70009562020-02-11 Eye metastasis in lung adenocarcinoma mimicking anterior scleritis: A case report Chen, Hua-Fei Wang, Wen-Xian Li, Xiao-Feng Wu, Li-Xin Zhu, You-Cai Du, Kai-Qi Xu, Chun-Wei World J Clin Cases Case Report BACKGROUND: The eye is a rare site for lung cancer metastasis. Indeed, ocular metastasis is one of the greatest challenges to quality of life in a cancer patient. Here we present a patient with lung adenocarcinoma and ocular metastasis. CASE SUMMARY: The patient was a 70-year-old man diagnosed with lung adenocarcinoma who developed eye metastasis mimicking anterior scleritis. Brain magnetic resonance imaging showed an abnormal signal in the right eye. Based on next generation sequencing of the surgical specimen, the patient was shown to have a KRAS point mutation (p.G12D). CONCLUSION: Multidiscipline expertise collaboration is needed to make the early diagnosis and determine the prompt treatment in patients. We hope to increase the awareness of the possibility of lung cancer metastasizing to the eye. Baishideng Publishing Group Inc 2020-01-26 2020-01-26 /pmc/articles/PMC7000956/ /pubmed/32047793 http://dx.doi.org/10.12998/wjcc.v8.i2.410 Text en ©The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved. http://creativecommons.org/licenses/by-nc/4.0/ This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial.
spellingShingle Case Report
Chen, Hua-Fei
Wang, Wen-Xian
Li, Xiao-Feng
Wu, Li-Xin
Zhu, You-Cai
Du, Kai-Qi
Xu, Chun-Wei
Eye metastasis in lung adenocarcinoma mimicking anterior scleritis: A case report
title Eye metastasis in lung adenocarcinoma mimicking anterior scleritis: A case report
title_full Eye metastasis in lung adenocarcinoma mimicking anterior scleritis: A case report
title_fullStr Eye metastasis in lung adenocarcinoma mimicking anterior scleritis: A case report
title_full_unstemmed Eye metastasis in lung adenocarcinoma mimicking anterior scleritis: A case report
title_short Eye metastasis in lung adenocarcinoma mimicking anterior scleritis: A case report
title_sort eye metastasis in lung adenocarcinoma mimicking anterior scleritis: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7000956/
https://www.ncbi.nlm.nih.gov/pubmed/32047793
http://dx.doi.org/10.12998/wjcc.v8.i2.410
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