Lipid Interactions of a Ciliary Membrane TRP Channel: Simulation and Structural Studies of Polycystin-2

Polycystin-2 (PC2) is a transient receptor potential (TRP) channel present in ciliary membranes of the kidney. PC2 shares a transmembrane fold with other TRP channels, in addition to an extracellular domain found in TRPP and TRPML channels. Using molecular dynamics (MD) simulations and cryoelectron...

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Detalles Bibliográficos
Autores principales: Wang, Qinrui, Corey, Robin A., Hedger, George, Aryal, Prafulla, Grieben, Mariana, Nasrallah, Chady, Baronina, Agnese, Pike, Ashley C.W., Shi, Jiye, Carpenter, Elisabeth P., Sansom, Mark S.P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7001106/
https://www.ncbi.nlm.nih.gov/pubmed/31806353
http://dx.doi.org/10.1016/j.str.2019.11.005

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