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Is tau in the absence of amyloid on the Alzheimer’s continuum?: A study of discordant PET positivity
The amyloid cascade model of Alzheimer’s disease posits the primacy of amyloid beta deposition preceding tau-mediated neurofibrillary tangle formation. The amyloid-tau-neurodegeneration biomarker-only diagnostic framework similarly requires the presence of amyloid beta for a diagnosis on the Alzheim...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7001143/ https://www.ncbi.nlm.nih.gov/pubmed/32051933 http://dx.doi.org/10.1093/braincomms/fcz046 |