Protective properties of heme oxygenase-1 expressed in umbilical cord mesenchymal stem cells help restore the ovarian function of premature ovarian failure mice through activating the JNK/Bcl-2 signal pathway-regulated autophagy and upregulating the circulating of CD8(+)CD28(−) T cells

BACKGROUND: Umbilical cord-derived mesenchymal stem cell (UCMSCs) transplantation has been widely studied in premature ovarian failure (POF). However, the underlying mechanism remains elusive. This study aims to investigate the protective properties and mechanisms of heme oxygenase-1 (HO-1) expresse...

Descripción completa

Detalles Bibliográficos
Autores principales: Yin, Na, Wu, Chenting, Qiu, Jianping, Zhang, Yueming, Bo, Le, Xu, Ying, Shi, Mengdie, Zhu, Songyue, Yang, Guangzhao, Mao, Caiping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7001243/
https://www.ncbi.nlm.nih.gov/pubmed/32019599
http://dx.doi.org/10.1186/s13287-019-1537-x

Ejemplares similares

Ejemplares similares