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H3F3A mutant allele specific imbalance in an aggressive subtype of diffuse midline glioma, H3 K27M-mutant

Diffuse midline glioma, H3 K27M-mutant is a lethal brain tumor located in the thalamus, brain stem, or spinal cord. H3 K27M encoded by the mutation of a histone H3 gene such as H3F3A plays a pivotal role in the tumorigenesis of this type of glioma. Although several studies have revealed comprehensiv...

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Detalles Bibliográficos
Autores principales: Maeda, Sachi, Ohka, Fumiharu, Okuno, Yusuke, Aoki, Kosuke, Motomura, Kazuya, Takeuchi, Kazuhito, Kusakari, Hironao, Yanagisawa, Nobuyuki, Sato, Shinya, Yamaguchi, Junya, Tanahashi, Kuniaki, Hirano, Masaki, Kato, Akira, Shimizu, Hiroyuki, Kitano, Yotaro, Yamazaki, Shintaro, Yamashita, Shinji, Takeshima, Hideo, Shinjo, Keiko, Kondo, Yutaka, Wakabayashi, Toshihiko, Natsume, Atsushi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7001313/
https://www.ncbi.nlm.nih.gov/pubmed/32019606
http://dx.doi.org/10.1186/s40478-020-0882-4