Exosome-shuttled miR-216a-5p from hypoxic preconditioned mesenchymal stem cells repair traumatic spinal cord injury by shifting microglial M1/M2 polarization

BACKGROUND: Spinal cord injury (SCI) can lead to severe motor and sensory dysfunction with high disability and mortality. In recent years, mesenchymal stem cell (MSC)-secreted nano-sized exosomes have shown great potential for promoting functional behavioral recovery following SCI. However, MSCs are...

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Detalles Bibliográficos
Autores principales: Liu, Wei, Rong, Yuluo, Wang, Jiaxing, Zhou, Zheng, Ge, Xuhui, Ji, Chengyue, Jiang, Dongdong, Gong, Fangyi, Li, Linwei, Chen, Jian, Zhao, Shujie, Kong, Fanqi, Gu, Changjiang, Fan, Jin, Cai, Weihua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7001326/
https://www.ncbi.nlm.nih.gov/pubmed/32019561
http://dx.doi.org/10.1186/s12974-020-1726-7

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