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Differential sorting behavior for soluble and transmembrane cargoes at the trans-Golgi network in endocrine cells
Regulated secretion of neuropeptides and peptide hormones by secretory granules (SGs) is central to physiology. Formation of SGs occurs at the trans-Golgi network (TGN) where their soluble cargo aggregates to form a dense core, but the mechanisms controlling the sorting of regulated secretory cargoe...
Autores principales: | Hummer, Blake H., Maslar, Drew, Soltero-Gutierrez, Margarita, de Leeuw, Noah F., Asensio, Cedric S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7001476/ https://www.ncbi.nlm.nih.gov/pubmed/31825717 http://dx.doi.org/10.1091/mbc.E19-10-0561 |
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