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The extent of Ssa1/Ssa2 Hsp70 chaperone involvement in nuclear protein quality control degradation varies with the substrate

Protein misfolding is a recurring phenomenon that cells must manage; otherwise misfolded proteins can aggregate and become toxic should they persist. To counter this burden, cells have evolved protein quality control (PQC) mechanisms that manage misfolded proteins. Two classes of systems that functi...

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Detalles Bibliográficos
Autores principales: Jones, Ramon D., Enam, Charisma, Ibarra, Rebeca, Borror, Heather R., Mostoller, Kaitlyn E., Fredrickson, Eric K., Lin, JiaBei, Chuang, Edward, March, Zachary, Shorter, James, Ravid, Tommer, Kleiger, Gary, Gardner, Richard G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7001477/
https://www.ncbi.nlm.nih.gov/pubmed/31825716
http://dx.doi.org/10.1091/mbc.E18-02-0121

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