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Electron tomography reveals aspects of spindle structure important for mechanical stability at metaphase

Metaphase spindles exert pole-directed forces on still-connected sister kinetochores. The spindle must counter these forces with extensive forces to prevent spindle collapse. In small spindles, kinetochore microtubules (KMTs) connect directly with the poles, and countering forces are supplied either...

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Detalles Bibliográficos
Autores principales: O’Toole, Eileen, Morphew, Mary, McIntosh, J. Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7001478/
https://www.ncbi.nlm.nih.gov/pubmed/31825721
http://dx.doi.org/10.1091/mbc.E19-07-0405