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HHV-7 U21 exploits Golgi quality control carriers to reroute class I MHC molecules to lysosomes

The human herpesvirus-7 (HHV-7) U21 glycoprotein binds to class I major histocompatibility complex (MHC) molecules in the endoplasmic reticulum (ER) and reroutes them to lysosomes. How this single viral glycoprotein efficiently redirects the U21/class I MHC complex to the lysosomal compartment is po...

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Detalles Bibliográficos
Autores principales:	Dirck, Aaron T., Whyte, Melissa L., Hudson, Amy W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The American Society for Cell Biology 2020
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7001482/ https://www.ncbi.nlm.nih.gov/pubmed/31851583 http://dx.doi.org/10.1091/mbc.E19-07-0363

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