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Quantitative digital pathology reveals association of cell-specific PNPLA3 transcription with NAFLD disease activity

BACKGROUND & AIMS: The I148M variant (rs738409) in patatin-like phospholipase domain-containing protein 3 (PNPLA3) is by far the most important genetic determinant of non-alcoholic fatty liver disease (NAFLD). However, in the context of NAFLD, the transcriptional regulation of PNPLA3 in human li...

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Detalles Bibliográficos
Autores principales:	Sandhu, Bynvant, Perez Matos, Maria C., Tran, Stephanie, Zhong, Alexander, Csizmadia, Eva, Kim, Misung, Herman, Mark A., Nasser, Imad, Lai, Michelle, Jiang, Z. Gordon
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2019
Materias:	Short Communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7001539/ https://www.ncbi.nlm.nih.gov/pubmed/32039370 http://dx.doi.org/10.1016/j.jhepr.2019.05.007

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