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HBeAg seroconversion is associated with a more effective PD-L1 blockade during chronic hepatitis B infection
BACKGROUND & AIMS: Current therapies for chronic hepatitis B virus (HBV) infection control viral replication but do not eliminate the risk of progression to hepatocellular carcinoma. HBV-specific CD8 T cells are necessary for viral control, but they are rare and exhausted during chronic infectio...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7001560/ https://www.ncbi.nlm.nih.gov/pubmed/32039367 http://dx.doi.org/10.1016/j.jhepr.2019.06.001 |